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A brief history of wheat utilization in China

Minxia LU, Liang CHEN, Jinxiu WANG, Ruiliang LIU, Yang YANG, Meng WEI, Guanghui DONG

《农业科学与工程前沿（英文）》 2019年 第6卷 第3期   页码 288-295 doi: 10.15302/J-FASE-2019266

摘要：

Wheat is one of the most important crops in both China and the world, and its domestication can be traced back to ~10000 years ago. However, the history of its origin and utilization in China remains highly ambiguous. Drawing upon the most recent results of taxonomic, genetic, archeological and textual studies focused on the wheat in prehistory, this paper argues that wheat was not domesticated but introduced into China in the late fifth millennium BP. In the subsequent centuries, this exotic crop was quickly utilized as a staple food in northwest China. In contrast, it was not adopted as a staple in Central Plains until the Han Dynasty (202 BCE–220 CE), which was mainly as a consequence of the living environment, population and innovations in food processing technology.

关键词： multidisciplinary evidence     prehistoric food globalization     wheat consumption     wheat domestication    

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Translating evidence into policy in China: opportunities and challenges

Jiyao Wang, Xuejuan Jin

《医学前沿（英文）》 2011年 第5卷 第3期   页码 315-320 doi: 10.1007/s11684-011-0146-6

摘要： Research and evidence are critical for the formulation of policies and practices in support of health care. In the past two decades, the Chinese Clinical Epidemiology Network has been promoting evidence-based policy making in China. Evidence-based policy has become a major part of the government’s approach to policy making. The current article addresses the translation of evidence into health policies based on the expansion of evidence-based medicine in China. It also discusses the opportunities and challenges for certain evidence to be considered in policy making and practice in the future.

关键词： clinical epidemiology     evidence-based decision making     policy    

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New practice in semaglutide on type-2 diabetes and obesity: clinical evidence and expectation

《医学前沿（英文）》 2022年 第16卷 第1期   页码 17-24 doi: 10.1007/s11684-021-0873-2

摘要： Obesity is an important risk factor of type 2 diabetes (T2D), which has become an important factor threatening human health. However, no perfect drug choice for obesity exists. Semaglutide is a kind of human glucagon-like peptide-1 (GLP-1) analog that promotes insulin secretion while inhibiting glucagon secretion through a glucose concentration-dependent mechanism. GLP-1 can also delay stomach emptying and suppress appetite to help lose weight. This review summarizes clinical evidence of the semaglutide effect on T2D and obesity and establishes expectations on future clinical trials for obesity treatment.

关键词： semaglutide     type 2 diabetes     obesity    

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Genetic evidence in planar cell polarity signaling pathway in human neural tube defects

null

《医学前沿（英文）》 2014年 第8卷 第1期   页码 68-78 doi: 10.1007/s11684-014-0308-4

摘要：

Neural tube defects (NTDs) are a group of birth anomalies having a profound physical, emotional, and financial effects on families and communities. Their etiology is complex, involving environmental and genetic factors that interact to modulate the incidence and severity of the developing phenotype. The planar cell polarity (PCP) pathway controls the process of convergent extension (CE) during gastrulation and neural tube closure and has been implicated in the pathogenesis of NTDs in animal models and human cohorts. This review summarizes the cumulative results of recent studies on PCP signaling pathway and human NTDs. These results demonstrate that PCP gene alterations contribute to the etiology of human NTDs.

关键词： planar cell polarity     neural tube defects     rare mutations    

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From SARS to MERS: evidence and speculation

null

《医学前沿（英文）》 2016年 第10卷 第4期   页码 377-382 doi: 10.1007/s11684-016-0466-7

摘要：

The Middle East respiratory syndrome coronavirus (MERS-CoV) is a novel zoonotic pathogen. In 2012, the infectious outbreak caused by MERS-CoV in Saudi Arabia has spread to more than 1600 patients in 26 countries, resulting in over 600 deaths. Without a travel history, few clinical and radiological features can reliably differentiate MERS from SARS. But in real world, comparing with SARS, MERS presents more vaguely defined epidemiology, more severe symptoms, and higher case fatality rate. In this review, we summarize the recent findings in the field of MERS-CoV, especially its molecular virology, interspecies mechanisms, clinical features, antiviral therapies, and the further investigation into this disease. As a newly emerging virus, many questions are not fully answered, including the exact mode of transmission chain, geographical distribution, and animal origins. Furthermore, a new protocol needs to be launched to rapidly evaluate the effects of unproven antiviral drugs and vaccine to fasten the clinical application of new drugs.

关键词： middle east respiratory syndrome     animal origin     cross-species transmission     monoclonal antibody    

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Electricity demand, GDP and employment: evidence from Italy

Cosimo MAGAZZINO

《能源前沿（英文）》 2014年 第8卷 第1期   页码 31-40 doi: 10.1007/s11708-014-0296-8

摘要： This paper applies time series methodologies to examine the causal relationship among electricity demand, real per capita GDP and total labor force for Italy from 1970 to 2009. After a brief introduction, a survey of the economic literature on this issue is reported, before discussing the data and introducing the econometric techniques used. The results of estimation indicate that one cointegrating relationship exists among these variables. This equilibrium relation implies that, in the long-run, GDP and labor force are correlated negatively, as well as GDP and electricity. Moreover, there is a bi-directional Granger causality flow between real per capita GDP and electricity demand; while labor force does not Granger-cause neither real per capita GDP nor electricity demand. This implies that electricity demand and economic growth are jointly determined at the same time for the Italian case. The forecast error variance decomposition shows that forecast errors in real per capita GDP are mainly caused by the uncertainty in GDP itself, while forecast errors in labor force are mainly resulted from the labor force itself, although aggregate income and electricity are important, too.

关键词： energy policies     electricity demand     GDP     labor force     stationarity     structural breaks     cointegration     causality     Italy    

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practice of accelerating transformation of traditional Chinese medicine from experience medicine to evidence-based

Baoyan Liu, Yanhong Zhang, Jingqing Hu, Liyun He, Xuezhong Zhou

《医学前沿（英文）》 2011年 第5卷 第2期   页码 163-170 doi: 10.1007/s11684-011-0143-9

摘要： The gradual development of Chinese medicine is based on constant accumulation and summary of experience in clinical practice, but without the benefit of undergoing the experimental medicine stage. Although Chinese medicine has formed a systematic and unique theory system through thousands of years, with the development of evidence-based medicine, the bondage of the research methods of experience medicine to Chinese medicine is appearing. The rapid transition and transformation from experience medicine to evidence-based medicine have become important content in the development of Chinese medicine. According to the features of Chinese medicine, we propose the research idea of “taking two ways simultaneously,” which is the study both in the ideal condition and in the real world. Analyzing and constructing the theoretical basis and methodology of clinical research in the real world, and building the stage for research technique is key to the effective clinical research of Chinese medicine. Only by gradually maturing and completing the clinical research methods of the real world could we realize “taking two ways simultaneously” and complementing each other, continuously produce scientific and reliable evidence of Chinese medicine, as well as transform and develop Chinese medicine from experience medicine to evidence-based medicine.

关键词： Chinese medicine     experience medicine     evidence-based medicine     real world    

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Identification of novel mutations in and in a family with craniofacial microsomia: evidence of digenic

《医学前沿（英文）》   页码 1006-1009 doi: 10.1007/s11684-023-1000-3

摘要： Identification of novel mutations in and in a family with craniofacial microsomia: evidence of digenic inheritance

关键词： family craniofacial microsomia     Identification novel mutations    

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Advances in COVID-19: the virus, the pathogenesis, and evidence-based control and therapeutic strategies

Guangbiao Zhou, Saijuan Chen, Zhu Chen

《医学前沿（英文）》 2020年 第14卷 第2期   页码 117-125 doi: 10.1007/s11684-020-0773-x

摘要： Since the outbreak of the COVID-19 pandemic in early December 2019, 81 174 confirmed cases and 3242 deaths have been reported in China as of March 19, 2020. The Chinese people and government have contributed huge efforts to combat this disease, resulting in significant improvement of the situation, with 58 new cases (34 were imported cases) and 11 new deaths reported on March 19, 2020. However, as of March 19, 2020, the COVID-19 pandemic continues to develop in 167 countries/territories outside of China, and 128 665 confirmed cases and 5536 deaths have been reported, with 16 498 new cases and 817 new deaths occurring in last 24 hours. Therefore, the world should work together to fight against this pandemic. Here, we review the recent advances in COVID-19, including the insights in the virus, the responses of the host cells, the cytokine release syndrome, and the therapeutic approaches to inhibit the virus and alleviate the cytokine storm. By sharing knowledge and deepening our understanding of the virus and the disease pathogenesis, we believe that the community can efficiently develop effective vaccines and drugs, and the mankind will eventually win this battle against this pandemic.

关键词： COVID-19     SARS-CoV-2     pathogenesis     evidence-based medicine     control and therapeutic strategies    

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Spillover effect of environmental investment: evidence from panel data at provincial level in China

Qunhui LIN, Guanyi CHEN, Wencui DU, Haipeng NIU

《环境科学与工程前沿（英文）》 2012年 第6卷 第3期   页码 412-420 doi: 10.1007/s11783-012-0392-0

摘要： This paper considers pollution density as a function of environmental investment. The higher environmental investment, the lower pollution density. The lower the pollution density is the higher production technology becomes. This is called the spillover effect. We collected China’s panel data at the provincial level from 2005 to 2009, and tested the spillover effect of environmental investment. This paper finds that the environmental investment influenced production technology positively. There is a significant positive relation between government expenditure and spillover effect.

关键词： environmental investment     spillover effect     endogenous growth    

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Exploring the methodology and application of clinical pathway in evidence-based Chinese medicine

Sicheng Wang, He Yu, Jianping Liu, Baoyan Liu

《医学前沿（英文）》 2011年 第5卷 第2期   页码 157-162 doi: 10.1007/s11684-011-0128-8

摘要： At present, clinical pathway has become one of the most important health care reform measures in many countries. In this study, the authors introduced basic concepts and explored the application of the clinical pathway of evidence-based Chinese medicine incorporated with the methodology from the concepts of management, evidence-based medicine, operational research and health economics. Such concepts provide examples and experiences, on which the application of clinical pathway in Chinese medicine practice in China can be based.

关键词： evidence-based medicine     clinical pathway     methodology     concept     technical difficulty    

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Evidence from Tunisian listed firms

Kaouther ZAABOUTI,Ezzeddine BEN MOHAMED,Abdelfettah BOURI

《能源前沿（英文）》 2016年 第10卷 第1期   页码 1-13 doi: 10.1007/s11708-016-0396-8

摘要： A new debate on the potential impact of oil price changes on the value of firms was initiated in this paper. Using a stochastic frontier approach, an attempt was made to derive the optimal value * of firms and calculate the value observed. Then the shortfall ( *– ) which represents the inefficiency term was explained. Starting from 19 industrial Tunisian firms listed on the Tunis Stock Exchange between 2007 and 2011, the fact that variation of oil prices can largely explain distortions in the value of firms was empirically demonstrated.

关键词： industrial Tunisian firms     oil price     value of firm     stochastic frontier approach    

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SOIL NITROGEN CYCLING AND ENVIRONMENTAL IMPACTS IN THE SUBTROPICAL HILLY REGION OF CHINA: EVIDENCE FROM

《农业科学与工程前沿（英文）》 2022年 第9卷 第3期   页码 407-424 doi: 10.15302/J-FASE-2022448

摘要：

● Soil nitrogen fluxes and influencing factors were reviewed in the subtropical hilly regions.

关键词： nitrogen cycling     soil nitrogen     nitrogen deposition     greenhouse gases emission     non-point source pollution     nitrogen use efficiency    

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航空发动机多学科设计优化技术研究

尹泽勇,米栋,吴立强,肖根升,刘飞春,李立君

《中国工程科学》 2007年 第9卷 第6期   页码 1-10

摘要：

多学科设计优化（MDO）是为实现复杂产品设计方法升级换代的最佳技术途径。针对先进航空发动 机设计面临的各学科间耦合关系复杂、指标冲突严重等困难，按零件、部件和总体方案设计３个阶段对MDO的 各项关键技术开展了研究、开发及应用工作，提出了基于MDO技术的航空发动机一体化设计方法。给出的５个工程应用实例表明，该方法与传统设计方法相比，能大幅提高航空发动机设计水平，具有广泛的工程应用前景。

关键词： 航空发动机设计     多学科设计优化     零件级优化     部件级优化     总体优化    

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Changes in public trust in physicians: empirical evidence from China

Dahai Zhao, Zhiruo Zhang

《医学前沿（英文）》 2019年 第13卷 第4期   页码 504-510 doi: 10.1007/s11684-018-0666-4

摘要： Studies examining the trends in public trust in physicians have provided a considerable amount of valuable policy implications for policymakers compared with cross-sectional studies on this topic in many countries. This study investigated changes in public trust in physicians in China based on two cross-sectional national surveys conducted in 2011 and 2016 and identified the determinants of these changes. The results indicated 83.4% of respondents in 2011 reported trust or strong trust in physicians in China, which decreased to 64.2% by 2016. The results of ordinal logistic regression demonstrated that public trust in physicians in China had decreased significantly from 2011 to 2016 ( <0.001) after adjusting for other independent variables. Self-reported health status, self-rated happiness, and self-identified social class were all associated positively with public trust in physicians in China. The results also confirmed that decreasing public satisfaction with the most recent treatment experience was the major determinant of decreasing public trust in physicians in China. The findings of this study suggest that decreasing public trust in physicians deserves considerable attention from national policymakers and that improving satisfaction with treatment experiences would be the most effective strategy for enhancing public trust in physicians in China.

关键词： trust in physicians     public trust     physician-patient relationship     health system performance    

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标题 作者 时间 类型 操作

A brief history of wheat utilization in China

Minxia LU, Liang CHEN, Jinxiu WANG, Ruiliang LIU, Yang YANG, Meng WEI, Guanghui DONG

期刊论文

Translating evidence into policy in China: opportunities and challenges

Jiyao Wang, Xuejuan Jin

期刊论文

New practice in semaglutide on type-2 diabetes and obesity: clinical evidence and expectation

期刊论文

Genetic evidence in planar cell polarity signaling pathway in human neural tube defects

null

期刊论文

From SARS to MERS: evidence and speculation

null

期刊论文

Electricity demand, GDP and employment: evidence from Italy

Cosimo MAGAZZINO

期刊论文

practice of accelerating transformation of traditional Chinese medicine from experience medicine to evidence-based

Baoyan Liu, Yanhong Zhang, Jingqing Hu, Liyun He, Xuezhong Zhou

期刊论文

Identification of novel mutations in and in a family with craniofacial microsomia: evidence of digenic

期刊论文

Advances in COVID-19: the virus, the pathogenesis, and evidence-based control and therapeutic strategies

Guangbiao Zhou, Saijuan Chen, Zhu Chen

期刊论文

Spillover effect of environmental investment: evidence from panel data at provincial level in China

Qunhui LIN, Guanyi CHEN, Wencui DU, Haipeng NIU

期刊论文

Exploring the methodology and application of clinical pathway in evidence-based Chinese medicine

Sicheng Wang, He Yu, Jianping Liu, Baoyan Liu

期刊论文

Evidence from Tunisian listed firms

Kaouther ZAABOUTI,Ezzeddine BEN MOHAMED,Abdelfettah BOURI

期刊论文

SOIL NITROGEN CYCLING AND ENVIRONMENTAL IMPACTS IN THE SUBTROPICAL HILLY REGION OF CHINA: EVIDENCE FROM

期刊论文

航空发动机多学科设计优化技术研究

尹泽勇,米栋,吴立强,肖根升,刘飞春,李立君

期刊论文

Changes in public trust in physicians: empirical evidence from China

Dahai Zhao, Zhiruo Zhang

期刊论文